Efficacy of rosuvastatin in treating patients with acute coronary syndromes complicated with arrhythmia and its influence on serum inflammatory factors
10.7619/jcmp.201803011
- VernacularTitle:瑞舒伐他汀治疗急性冠脉综合征合并心律失常的疗效及其对血清炎性因子的影响
- Author:
Zhenhe LAN
1
;
Jing MA
;
Jinxia ZHAO
Author Information
1. 辽宁省阜新市第二人民医院(妇产医院)
- Keywords:
rosuvastatin;
acute coronary syndrome;
arrhythmia;
inflammatory factors
- From:
Journal of Clinical Medicine in Practice
2018;22(3):41-43,47
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the clinical efficacy of rosuvastatin in the treatment of patients with acute coronary syndrome complicated with arrhythmia and its influence on serum inflammatory factors.Methods A total of 96 patients with acute coronary syndromes complicated with arrhythmia were selected and randomly divided into observation group and control group,48 cases in each group.The patients in the control group were treated with lovastatin,while the patients in the observation group were treated with rosuvastatin.The levels of inflammatory factors,apoptosis and drug-induced adverse reactions were compared between the two groups.Results After treatment,the levels of IL-18,TNF-α,hs-CRP and C-myc,Bcl-2 protein improved significantly in both groups,and these indexes in observation group were significantly better than control group (P ＜ 0.05).There was no significant difference in incidence rate of adverse reactions between the two groups (P ＞0.05).Conclusion Rosuvastatin is effective and safe in the treatment of patients with acute coronary syndrome complicated with arrhythmia.
