Clinical Study on Modified Qingying Decoction in Treating Endotoxemia in Cirrhosis due to Hepatitis B of Toxic Heat and Blood Stasis Syndrome
10.14148/j.issn.1672-0482.2016.0322
- VernacularTitle:加减清营汤治疗乙肝后肝硬化内毒素血症热毒血瘀型的临床研究
- Author:
Kang-Wan TU
1
;
Yin-Fang ZHU
;
Ping YU
;
Qin TANG
;
Zhi-Han YAN
Author Information
1. 无锡市第五人民医院中西医结合科
- Keywords:
modified Qingying Decoction;
cirrhosis due to hepatitis B;
endotoxemia;
toxic heat and blood stasis syndrome
- From:
Journal of Nanjing University of Traditional Chinese Medicine
2016;32(4):322-325
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To study the effects of modified Qingying Decoction on endotoxin levels of patients with cirrhosis endotoxemia due to hepatitis B.METHODS 58 patients with cirrhosis endotoxemia due to hepatitis B of toxic heat and blood stasis syndrome were randomly divided into treatment group(30 cases) and control group(28 cases).Patients in the control group were treated with hepatoprotective medication therapy,including reduced glutathione injection,Kuhuang injection and diammonium glycyrrhizinate and sodium chloride injection.Based on this,patients in the treatment group were further given Qingying Decoction.The endotoxin levels in the serum of these 58 patients were tested using the dynamic turbidity method,to-gether with serum alanine aminotransferase(ALT),total bilirubin(TBiL) and prothrombin time(PT).RESULTS The treat-ment group was superior to the control group in decreasing clinical symptom integral(P <0.01) and even more superior in re-ducing endotoxin levels(P <0.05).CONCULSION Qingying Decoction has a notable curative effect on cirrhosis endotoxemia due to hepatitis B.