Systemic Evaluation on Clinical Research of Dispersing Lung Method in Treating Bronchial Asthma Based on Meta Analysis
10.14148/j.issn.1672-0482.2016.0245
- VernacularTitle:基于 Meta 分析的宣肺法治疗支气管哮喘临床研究系统评价
- Author:
Ing Jing-j ZHANG
1
;
Xin-Sheng FAN
;
Jun-Qin WANG
Author Information
1. 南京中医药大学基础医学院
- Keywords:
bronchial asthma;
dispersing lung method;
Meta analysis;
systemic evaluation;
evidence-based medicine
- From:
Journal of Nanjing University of Traditional Chinese Medicine
2016;32(3):245-249
- CountryChina
- Language:Chinese
-
Abstract:
ABSTRAT:OBJECTIVE To systematically evaluate the efficiency of dispersing lung method in treating acute attack of bron-chial asthma.METHODS Relevant data were retrieved from Chinese Journal Full Text Database(CNKI),Chinese Science and Technology Journals Full Text Database(VIP),Wan Fang data online knowledge service platform,Chinese Biomedical Litera-ture Database(CBM),Cochrane Library,Medline and Embase.Randomized controlled trials(RCTs)and semi-randomized con-trolled trials(CCTs) concerning acute attack of bronchial asthma treated with dispersing lung method were included,methodo-logical quality were assessed based on improved Jadad evaluation criteria and Stata10.0 software was used for statistical analy-sis.RESULTS A total of 1 1 18 subjects from 7 RCTs and 7 CCTs met the inclusion criteria.The Meta analysis showed that traditional Chinese medicine combined with conventional western medicine therapy in RCTs were superior to simple western treatment(OR =5.1 6,95% CI[2.67,9.97],P <0.05).Compared to control group,curative effects of traditional Chinese medicine group in CCTs were better(RR =1.1 5,95% CI[1.09,1.23],P <0.05).Publication bias was found in CCTs,not in RCTs.CONCLUSION Dispersing lung method has certain advantages over western medicine therapy in the treatment of bronchial asthma,and the quality of clinical research deserves further research.
