Determination of 4-methyl-2-pentanol in workplace air by solvent desorption-gas chromatography
10.3760/cma.j.cn121094-20230103-000001
- VernacularTitle:工作场所空气中4-甲基-2-戊醇测定的溶剂解吸-气相色谱法
- Author:
Guanlin CHEN
1
;
Qiang TAN
;
Yaoji FENG
;
Hongjun LAN
;
Xuewang YANG
;
Xueqiong ZHOU
Author Information
1. 佛山市职业病防治所，佛山市职业健康研究院检验科，佛山 528000
- Keywords:
Chromatography, gas;
4-Methyl-2-pentanol;
Workplace;
Air;
Solvent desorption
- From:
Chinese Journal of Industrial Hygiene and Occupational Diseases
2023;41(10):859-862
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To establish a method for the determination of 4-methyl-2-pentanol in the air of workplace by gas chromatography.Methods:In January 2022, 4-methyl-2-pentanol in the air of workplace was collected by activated carbontube, eluted with dichloromethane-methanol (95∶5, V/ V), separated by capillary column and determined by gas chromatogram. Results:The limit of detection for 4-methyl-2-pentanol was 0.04 μg/ml. The linear range of 4-methyl-2-pentanol was 0.16-1616.60 μg/ml, with the regression equation of y=1.94 x-5.48, and the coefficient correlation was 0.99958, and the minimum detection concentration was 0.03 mg/m 3 (collected sample volume was 1.50 L). The within-run precisions were 1.08%-1.75% and the between-run precisions were 1.41%-2.52%. The desorption rates were 95.15%-99.91%. The samples could be stored at least 3 days at room temperature and 7 days at 4 ℃ without significant loss. Conclusion:The method has the advantages of good precision, high sensitivity and simple operation. It is suitable for the determination of 4-methyl-2-pentanol in the air of workplace.
