Research of mother-to-infant transmission of human papilloma virus infection during pregnancy
10.7619/jcmp.201723017
- VernacularTitle:妊娠期人乳头状瘤病毒感染的母婴传播的研究
- Author:
Xianghua YIN
1
;
Dan LU
;
Min JIANG
;
Yehua JING
;
Lijuan YANG
Author Information
1. 江苏省苏北人民医院妇产科
- Keywords:
human papilloma virus;
pregnancy,mother-to infant transmission,effect on fetus and infants
- From:
Journal of Clinical Medicine in Practice
2017;21(23):57-59
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the possible routes of mother-to-infant transmission of human papilloma virus (HPV) during pregnancy and its influence on fetuses and infants.Methods A total of 175 HPV-positive pregnant women were selected as study group and 344 HPV-negative pregnant women in the same period were as control group.The pregnant outcomes and neonatal infection rates of two groups were studied.Results The rate of HPV infection in the study group was 6.86％ (12/175).There were no significant difference in HPV detection rate regarding amniotic fluid,placenta,postpartum milk,neonatal umbilical cord blood and throat secretion in the study group by vaginal delivery and cesarean section.The outcomes of HPV-positive pregnancy such as spontaneous abortion,premature delivery,premature rupture of fetal membrane,limited fetal growth,and neonatal respiratory distress syndrome were significantly higher in the study group than that of the control group.The rupture of membranes time was related to the neonatal infection of HPV.Conclusion The transmission of HPV in mother-to-child transmission cannot be completely avoided by delivery modes.It can also be transmitted vertically through the cord blood,blood,amniotic fluid and placenta,and horizontally by breast feeding.
