A case of severe rhabdomyolysis after γ-butyrolactone withdrawal

VernacularTitle:γ-丁内酯戒断后致严重横纹肌溶解1例
Author: Wenjie WANG ¹ ; Houqing LU
Author Information

1. 铜陵市人民医院重症医学科，铜陵　244000
Keywords: Substance withdrawal syndrome; γ-butyrolactone; Rhabdomyolysis
From: Chinese Journal of Industrial Hygiene and Occupational Diseases 2022;40(7):537-538
CountryChina
Language:Chinese
Abstract: γ-butyrolactone is a colorless transparent liquid used in the production of drugs such as cyclopropylamine and pyrrolidone, and is also used as an industrial solvent, diluent, curing agent, etc., and is listed as the third category of precursor chemicals control. There is less clinical exposure to γ-butyrolactone and insufficient studies on its withdrawal response. This article reports a case of severe life-threatening rhabdomyolysis in a patient with γ-butyrolactone withdrawal. After active treatment, the patient eventually recovered. The clinical characteristics and treatment methods of γ-butyrolactone withdrawal reaction were summarized, suggesting that severe withdrawal reaction may occur in γ-butyrolactone.