Clinical Research of Chailong Jieyu Pill in Treating Generalized Anxiety Disorder
10.14148/j.issn.1672-0482.2015.0214
- VernacularTitle:柴龙解郁丹治疗广泛性焦虑症的临床研究
- Author:
Guang-Kui FENG
1
;
Yin-Yi CHEN
;
Le-Jun LI
;
Xian-Jun MA
;
Guang-Rong BIAN
;
Xiang-Yong LI
;
Jie-Chun CHEN
Author Information
1. 南京中医药大学连云港附属医院
- Keywords:
generalized anxiety disorder;
stagnation of liver qi;
Chailong Jieyu pill;
placebo;
clinical research
- From:
Journal of Nanjing University of Traditional Chinese Medicine
2015;(3):214-217
- CountryChina
- Language:Chinese
-
Abstract:
ABSTRACT:OBJECTIVE To explore the clinical efficacy and safety of Chailong Jieyu pill in treating generalized anxiety dis-order(Stagnation of liver qi syndrome).METHODS A six-week randomized,double-blind,placebo-controlled study was con-ducted on 60 patients with the diagnosis of generalized anxiety disorder(Stagnation of liver qi syndrome).The treatment group took Chailong Jieyu pill orally,every 6g,3 times a day.And then Hamiltonanxietyscale (HAMA),TCMsymptomcustom-scale,Side reaction scale(TESS) were observed.RESULTS The score of HAMA and TCM symptom custom scale in the treatment group had a significant and progressive effect(P <0.01),and were better than that in the control group(P <0.01) after 2 weeks,4 weeks and 6 weeks.For HAMA,the total effective rate of the treatment group was 93.10%,better than that of the control group which was 32.26%(P <0.01).For TCM symptom custom scale,the total effective rate of the treatment group was 93.10%,better than that of the control group which was 29.03% (P <0.01).The every score of TCM symptom custom scale in the treatment group had significant differences after treatment(P <0.01),while score in the control group on-ly had a statistic significance on the symptom of irritability(P <0.05).The comparison between the groups had a significant difference on the symptoms of irritability,sigh,palpitation and dizziness(P <0.01).The score of TESS had no statistic sig-nificance(P >0.05).CONCLUSION Chailong Jieyu Pill is effective and safe and has little side effect,high compliance in treating generalized anxiety disorder(Stagnation of liver qi syndrome).
