Effect of Jianpi Yangzheng Xiaozheng Fang on Survival and Life Quality of Cases with Late Stage Gastric Cancer
10.14148/j.issn.1672-0482.2015.0201
- VernacularTitle:健脾养正消癥方对胃癌患者晚期生存期和生活质量的影响
- Author:
Xi ZOU
1
;
Yu-Chao CHEN
;
Shou-You HU
;
Rui-Ping WANG
;
Xiao-Xiao WANG
;
Shen-Lin LIU
;
Bao-Rui LIU
;
Jian-Wei LU
Author Information
1. 南京中医药大学附属医院
- Keywords:
Jianpi Yangzheng Xiaozheng Fang;
late stage gastric cancer;
survival;
life quality
- From:
Journal of Nanjing University of Traditional Chinese Medicine
2015;(3):201-205
- CountryChina
- Language:Chinese
-
Abstract:
ABSTRACT:OBJECTIVE To explore the effect of Jianpi Yangzheng Xiaozheng Fang on survival and life quality of cases with late stage gastric cancer.METHODS Two hundred and thirty-two cases were randomly divided into experiment group and control group.The former was given combined treatment of Jianpi Yangzheng Xiaozheng Fang and chemotherapy,while the latter was treated with chemotherapy only.Survival,clinical symptom score and life quality score were compared between two groups.RESULTS Cases in experiment group survived longer than that of control group,with average days of(327±15.33), while the average survival was (257± 16.56) in control group.There was statistical significance between them (P <0.01). Life quality was compared between two groups through QLQ-C30 scale,which showed that such symptoms as mood function, role function,pain,nausea and vomiting,fatigue and poor appetite and general health got better improvement in experiment group.Statistical significance can be found between them(P <0.05).Comparison of symptoms score from perspective of tra-ditional Chinese medicine between both groups also indicated statistical significance(P <0.05),as the improvement of gastric pain,poor appetite,fatigue and got better improvement in experiment group.CONCLUSION Combined treatment of Jianpi Yangzheng Xiaozheng Fang and chemotherapy is effective in prolonging survival,improving gastric pain and life quality for ca-ses with late stage gastric cancer.