Cumulative noise exposure and the risk of high-frequency hearing loss relationships
10.3760/cma.j.cn121094-20200619-00347
- VernacularTitle:累积噪声暴露量与高频听力损失剂量反应关系的Meta分析
- Author:
Jing CHEN
1
;
Jiabing WU
;
Kun WU
;
Jianru ZHENG
;
Liangying MEI
;
Yong MEI
Author Information
1. 442000 十堰市职业病防治院
- Keywords:
Cumulative noise exposure;
High frequency hearing loss;
Dose-response relationship;
Meta analysis
- From:
Chinese Journal of Industrial Hygiene and Occupational Diseases
2021;39(12):919-924
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the dose-response relationship between cumulative noise exposure and high-frequency hearing loss, and further to provide a basis for the control of occupational hazards of noise.Methods:A Meta-analysis of dose-response relationships was performed on the data of eligible literatures published in China from January 2000.1 to December 2019.12.Results:The initial combined Odds Ratio ( OR) and its 95%CI in the Meta-analysis were 1.10 (1.08-1.12) . As the Begg's funnel plot and Egger's test indicated publication bias ( t=5.97, P<0.01) , the Trim-and-Fill Method was used for OR value adjustment. The adjusted-OR was 1.09 (1.07-1.12) ; sensitivity analysis showed that the results of this Meta-analysis have high stability; subgroup analysis indicated that the ORs of the steady-state noise group and the non-steady-state noise group were 1.10 (1.08-1.12) and 1.14 (1.07-1.21) , the ORs of the old standard group and the new standard group were 1.10 (1.08-1.12) and 1.11 (1.00-1.24) , respectively. The nonlinear dose-response relationship curve demonstrated that the risk of high-frequency hearing loss increases rapidly after CNE reaches 95 dB (A) ·years. Conclusion:There is a definite dose-response relationship between CNE and high-frequency hearing loss, which can be used to predict the risk of high-frequency hearing loss in noisy workers.
