Vigilance against a highly lethal insecticide chlorfenapyr poisoning (report of 4 cases and literature review)
10.3760/cma.j.cn121094-20210513-00251
- VernacularTitle:警惕高致死性杀虫剂虫螨腈中毒（附四例病例及文献复习）
- Author:
Yu GONG
1
;
Qingbing MENG
;
Liang LIU
;
Yaqing AN
;
Rui ZHANG
;
Yiqing SUN
;
Jianling SU
;
Yingping TIAN
Author Information
1. 050000 石家庄，河北医科大学第二医院急诊科
- Keywords:
Insecticides;
Poisoning;
Chlorfenapyr;
Emamectin benzoate·chlorfenapyr;
Sodium pentachlorophenol
- From:
Chinese Journal of Industrial Hygiene and Occupational Diseases
2021;39(9):689-693
- CountryChina
- Language:Chinese
-
Abstract:
In order to improve the clinical attention to the poisoning of chlorfenapyr, the diagnosis and treatment strategy of chlorfenapyr poisoning were discussed. This paper collected 4 cases of chlorfenapyr in the emergency department of the Second Hospital of Hebei Medical University and 4 cases of literature review, summarized the clinical characteristics of pesticide poisoning cases containing chlorfenapyr in China, and summarized and analyzed the clinical data of the cases. Seven of the 8 patients died from poisoning by chlorfenapyr. Exposure to chlorfenapyr through respiratory tract and digestive tract showed high mortality. Fever, hyperhidrosis, elevated muscle enzymes and progressive central nerve damage were its prominent clinical characteristics. Most of the initial symptoms of exposure were not serious. Some patients, especially those with low exposure dose, had a relatively stable stage with or without clinical diagnosis and treatment. In case of sweating, obvious fever and disturbance of consciousness, the condition would deteriorate rapidly, respiratory and circulatory failure and eventually die. With the increase of production capacity and market launch, people have more opportunities to be exposed to chlorfenapyr. It is urgent to strengthen the basic and clinical research of chlorfenapyr poisoning; Attention should be paid to the observation and treatment in the initial stable stage of poisoning, which can be used as a reference for the treatment of oxidative phosphoric acid dissolving coupling agent (sodium pentachlorophenol) poisoning.
