Effect of laparoscopic and open extended radical resection of rectal carcinoma on cellular immune function of elderly patients
10.7619/jcmp.201717002
- VernacularTitle:腹腔镜与开腹直肠癌扩大根治术对老年患者细胞免疫功能的影响
- Author:
Zhengyao LYU
1
;
Zhiguo XIONG
;
Ding DING
;
Yingxin XU
Author Information
1. 湖北省武穴市第三人民医院普外科
- Keywords:
laparoscopy;
open extended radical resection of rectal carcinoma;
cellular immune function;
elderly patients
- From:
Journal of Clinical Medicine in Practice
2017;21(17):6-8
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of laparoscopic and open extended radical resection of rectal carcinoma on cellular immune function of elderly patients.Methods A total of 60 elderly patients with colorectal cancer were enrolled and divided into two groups according to therapeutic methods.The control group was treated with open extended radical resection of rectal carcinoma,and the study group was treated with laparoscopic extended radical resection of rectal carcinoma.The fasting venous blood of all patients 1 day before operation and 1,3 and 5 days after operation were measured,and the levels of T lymphocyte subsets (CD3 +,CD4 +,CD8 +) were measured and compared.Results Compared with the levels of indexes 1 day before operation,CD3 +,CD4 +,CD8 + in the control group 1,3 and 5 days after operation and 1,3 days after operation in study group significantly decreased (P ＜ 0.05).The 1,3 and 5 days after operation,the CD3 +,CD4 + and CD8 + in study group were significantly higher than the control group (P ＜ 0.05).Conclusion Laparoscopic and open extended radical resection of rectal carcinoma have a certain impact on cellular immune function,but effect of laparoscopic extended radical resection of rectal carcinoma is relatively less,which is conducive to the orotection of cellular immune function.
