Determination of bisphenol S in urine by vortex-assisted liquid-liquid microextraction with high performance liquid chromatography
10.3760/cma.j.cn121094-20191010-00484
- VernacularTitle:尿中双酚S测定的涡旋辅助液液微萃取-高效液相色谱法
- Author:
Yingying GU
1
;
Yong MEI
;
Yumeng REN
;
Jun HAN
Author Information
1. 430065 武汉科技大学医学院公共卫生学院，职业危害识别与控制湖北省重点实验室
- Keywords:
Liquid-liquid microextraction;
Chromatography;
Bisphenol S
- From:
Chinese Journal of Industrial Hygiene and Occupational Diseases
2021;39(1):51-54
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To establish a method for the determination of bisphenol S in urine using dispersive liquid-liquid microextraction (DLLME) coupled with high performance liquid chromatography (HPLC) .Methods:The acetonitrile, octanol were used as extraction solvent, dispersive solvent respectively, for the preconcentration of bisphenol S. The optimal extraction conditions were optimized by single factor rotations, and methodological performance index were tested.Results:The linear correlation coefficient of bisphenol S in the range of 0.0-160 μg/L is greater than 0.999. The detection limit of this method was 0.76 μg/L, and the recovery rates were 88.06%-103.81%. The intra-and inter-day precisions were 1.78%-2.85% and 2.65%-4.25%, respectively.Conclusion:The method is reliable and sensitive. It is suitable for the determination of bisphenol S in urine samples for occupational exposure populations and non-professional.
