Clinical analysis of 11 cases of sub-acute arsenic poisoning

VernacularTitle:亚急性砷中毒11例临床分析
Author: Juan YUAN ¹ ; Yan LAI ; Chuntao HUANG ; Lei HUANG ; Fangkun TANG ; Lun HONG ; Yimei YANG
Author Information

1. 410007　长沙，湖南省职业病防治院
Keywords: arsenic; arsenism; arsenic dermatitis; toxic peripheral neuropathy
From: Chinese Journal of Industrial Hygiene and Occupational Diseases 2020;38(12):921-924
CountryChina
Language:Chinese
Abstract: Objective:To investigate the clinical manifestations, treatments and prognosis of subacute arsenic poisoning.Methods:In January 2020, a retrospective analysis was carried out on 11 patients hospitalized with subacute arsenic poisoning caused by arsenic contaminated drinking water. We observed manifestations, treatments and prognosis.Results:The main clinical presentations of subacute arsenic poisoningin were gastroenteritis in early phase, some of them had other organ damage, such as skin, blood, liver, kidney, cardiovascular and so on. The later phase was mainly peripheral nervous system damage. The treatment was mainly to chelate arsenic, protect target organs and treat toxic peripheral neuropathy. Most were significantly recoveried, but the recovery of severe toxic peripheral neuropathy was tardy.Conclusion:Acute gastroenteritis is the mainly early manifestation of subacute arsenic poisoning caused by digestive tract, and toxic peripheral neuropathy in the later phase. The prognosis is good, but the recovery of severe toxic peripheral neuropathy is tardy.