Clinical research for chronic obstructive pulmonary disease patients with respiratory failure treated by bronchoalveolar lavage combined with non-invasive positive pressure ventilation
10.7619/jcmp.201712008
- VernacularTitle:支气管肺泡灌洗联合无创正压通气治疗慢性阻塞性肺疾病合并呼吸衰竭的临床研究
- Author:
Jinru WU
1
;
Xiansheng ZENG
Author Information
1. 湖北省襄阳市中心医院 呼吸二科
- Keywords:
chronic obstructive pulmonary disease;
respiratory failure;
bronchoalveolar lavage;
non-invasive positive pressure ventilation
- From:
Journal of Clinical Medicine in Practice
2017;21(12):25-28
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical value of bronchoalveolar lavage (BAL) combined with noninvasive positive pressure ventilation (NIPPV) for chronic obstructive pulmonary disease patients with respiratory failure.Methods A total of 104 chronic obstructive pulmonary disease patients with respiratory failure in our hospital were randomly divided into control group (conventional treatment group) and observation group (BAL+NIPPV treatment group).Arterial blood gas values of two groups before and after the treatment, 2 hours, 12 hours and 24 hours after treatment were compared, and the incidence of adverse reactions of two groups during treatment was analyzed.Results The PH value was significantly increased at 24 h after treatment in both groups, the difference was statistically significant (P<0.05).Compared with treatment before, p(CO2) was significantly decreased, and p(O2) was increased obviously at each time point, and the improvement of observation group was better than the control group, the differences were statistically significant (P<0.05).The incidence of adverse reactions in tracheal intubation, abdominal distension and nasal and farcical bruise of two groups showed a significant difference in two groups(P<0.05).Conclusion BAL combined with NIPPV can significantly improve patients''p(O2), reduce p(CO2), and improve blood PH value, effectively improve the patient''s symptoms of respiratory failure, and correct the acid-base imbalance, so it worthy of clinical popularization and application.
