Effect of nasal continuons positive airway pressure combined with pulmonary surfactant on treating 14 premature infants with respiratory distress syndrome
10.7619/jcmp.201711033
- VernacularTitle:经鼻持续气道正压通气联合肺表面活性物质治疗呼吸窘迫综合征早产儿14例
- Author:
Yanrong ZHAO
1
;
Shuqing ZHAO
;
Min MIN
Author Information
1. 北京怀柔医院 儿科
- Keywords:
respiratory distress syndrome;
nasal continuons positive airway pressure (NCPAP);
pulmonary surfactant;
premature infant
- From:
Journal of Clinical Medicine in Practice
2017;21(11):111-114
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect of nasal continuons positive airway pressure (NCPAP) combined with pulmonary surfactant for premature infants with respiratory distress syndrome.Methods A total of 28 premature infants with respiratory distress syndrome were divided into MV group with 14 patients given mechanical ventilation therapy and conventional assisted pulmonary surfactant therapy,and NCPAP group with 14 patients given nasal continuous positive airway pressure therapy and pulmonary surface active treatment,clinical efficacy were analyzed.Results With the treatment time prolonging,compared with treatment indices before,pH value p(O2) and p(O2)/FiO2 levels after treatment increased at 6,12,24 h,and p(CO2) decreased,the symptoms of patients was improved significantly (P<0.05);After treatment,heart rate,respiratory frequency,average oxygen index and other signs were improved significantly,the disease almost returned to normal.There was significant difference in above indicators in two groups(P<0.05);The NCPAP rate was 85.71%,which was higher than 64.29% of MV group (P<0.05);Incidence of adverse reaction was 14.28% in NCPAP group,and 35.71% in MV group,and there was significant difference in the incidence of adverse reactions between the two groups (P<0.05).Conclusion NCPAP combined with pulmonary surfactant therapy can effectively improve life quality of children with respiratory distress syndrome in premature children,improve efficacy,and reduce complications.
