Effect of bronchoalveolar lavage combined with mechanical ventilation on clinical symptoms and lung function of elderly patients with severe asthma
10.7619/jcmp.201711014
- VernacularTitle:肺泡灌洗术联合机械通气对老年重症哮喘患者临床症状及肺功能的影响
- Author:
Minghua ZHANG
1
;
Mingming SHUI
;
Jun YAO
;
Wanli FAN
Author Information
1. 湖北省恩施土家族苗族自治州中心医院
- Keywords:
severe asthma;
bronchoalveolar lavage;
mechanical ventilation;
lung function;
inflammatory mediators
- From:
Journal of Clinical Medicine in Practice
2017;21(11):45-47
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect of bronchoalveolar lavage combined with mechanical ventilation on the clinical symptoms and pulmonary function of elderly patients with severe asthma.Methods A total of 70 patients with severe asthma were selected and randomly divided into observation group and control group.The observation group was given routine treatment,bronchoalveolar lavage and mechanical ventilation,while the control group was given routine treatment and mechanical ventilation.Clinical symptoms,airway function,inflammatory mediators and effect were compared between two groups.Results The effective rate of observation group was 94.29%,which was significantly higher than 77.14% of control group (P<0.05).Clinical symptoms,duration of mechanical ventilation and ICU stay of observation group were significantly shorter than the control group (P<0.05).In the observation group,FEV1,FVC and FEV1/FVC% were significantly higher than the control group (P<0.05),and CRP,TNF-α and IL-6 were significantly lower than the control group (P<0.05).Conclusion Bronchoalveolar lavage combined with mechanical ventilation can improve the clinical symptoms and pulmonary function,alleviate the inflammatory reaction and improve the therapeutic effect.
