Biomarkers for Primary Sjo¨ gren’s Syndrome
- Author:
Chen WEIQIAN
1
;
Cao HENG
;
Lin JIN
;
Olsen NANCY
;
Zheng Guo SONG
Author Information
1. Division of Rheumatology
- Keywords:
Biomarker;
Fms-like tyrosine kinase 3 ligand;
Myxovirus-resistance protein A;
Non-coding RNAs;
Saliva;
Sjogren syndrome
- From:
Genomics, Proteomics & Bioinformatics
2015;(4):219-223
- CountryChina
- Language:Chinese
-
Abstract:
Primary Sjogren’s syndrome (pSS) is a systemic autoimmune disease with exocrine gland dysfunction and multi-organ involvement. Recent progress in understanding the pathogenesis of pSS offers an opportunity to find new biomarkers for the diagnosis and assessment of disease activity. Screening noninvasive biomarkers from the saliva and tears has significant potential. The need for specific and sensitive biomarker candidates in pSS is significant. This review aims to summarize recent advances in the identification of biomarkers of Sjogren syndrome, trying to identify reliable, sensitive, and specific biomarkers that can be used to guide treatment decisions.
