Application of Next-generation Sequencing Technology in Forensic Science
10.1016/j.gpb.2014.09.001
- Author:
Yang YARAN
1
;
Xie BINGBING
;
Yan JIANGWEI
Author Information
1. CAS Key Laboratory of Genome Sciences and Information
- Keywords:
Forensics;
Next-generation sequencing;
Genomics;
Degradation of DNA
- From:
Genomics, Proteomics & Bioinformatics
2014;(5):190-197
- CountryChina
- Language:Chinese
-
Abstract:
Next-generation sequencing (NGS) technology, with its high-throughput capacity and low cost, has developed rapidly in recent years and become an important analytical tool for many genomics researchers. New opportunities in the research domain of the forensic studies emerge by harnessing the power of NGS technology, which can be applied to simultaneously analyzing multi-ple loci of forensic interest in different genetic contexts, such as autosomes, mitochondrial and sex chromosomes. Furthermore, NGS technology can also have potential applications in many other aspects of research. These include DNA database construction, ancestry and phenotypic inference, monozygotic twin studies, body fluid and species identification, and forensic animal, plant and microbiological analyses. Here we review the application of NGS technology in the field of forensic science with the aim of providing a reference for future forensics studies and practice.
