Effect of dexmedetomidine combined with sufentanil on postoperative analgesia foRpatients with orthopedic surgery
10.7619/jcmp.201709029
- VernacularTitle:右美托咪定联合舒芬太尼在骨科手术后镇痛中的效果
- Author:
Huifang SUN
1
;
Boxiong SHEN
;
Haiming LUO
Author Information
1. 上海第九人民医院北部 麻醉科
- Keywords:
orthopedic surgery;
sufentanil;
dexmedetomidine;
postoperative analgesia
- From:
Journal of Clinical Medicine in Practice
2017;21(9):113-115,122
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effect of dexmedetomidine combined with sufentanil on postoperative analgesia foRpatients with orthopedic surgery.Methods A total of 86 patients with orthopedic surgery were randomly divided into observation group and control group.The patients in the observation group were treated with dexmedetomidine combined with sufentanil foRpostoperative analgesia.The control group was treated with sufentanil foRpostoperative analgesia.The VAS and quantitative sensory testing (QST) were performed at different time points in both groups.The numbeRof postoperative patient-controlled analgesia,hemodynamics parameters,the adverse reaction and satisfaction degree were compared between the two groups.Results The VAS scores at T1 to T6 in control group were significantly higheRthan the observation group,the mechanical pain threshold was significantly loweRthan the observation group,and the HRand MAP were significantly higheRthan the observation group (P<0.05).The numbeRof patient-controlled analgesia,the dosage of sufentanil and the incidence rate of adverse reactions were significantly higheRin the control group than the observation group (P<0.05).The satisfactory degree of the observation group was significantly higheRthan the control group (P<0.05).Conclusion Dexmedetomidine can reduce the dosage of sufentanil and the incidence rate of side effects in treatment of patients with orthopedic surgery.
