Host Proteome Research in HIV Infection

Author: Zhang LIJUN ^{1
,

2} ; Zhang XIAOJUN ; Ma QING ; Zhou HONGHAO
Author Information

1. Department of Pharmacogenetics,Institute of Clinical Pharmacology,Central South University,Changsha 410078,China
2. Shanghai Public Health Clinical Center,Fudan University,Shanghai 201508,China
Keywords: proteomics; HIV; biomarker; HIV-host interaction
From: Genomics, Proteomics & Bioinformatics 2010;8(1):1-9
CountryChina
Language:Chinese
Abstract: Proteomics has been widely used in the last few years to look for new biomarkers and decipher the mechanism of HIV-host interaction.Herein,we review the recent developments of HIV/AIDS proteomic research,including the samples used in HIV/AIDS related research,the technologies used for proteomic study,the diagnosis biomarkers of HIV-associated disease especially HIV-associated neurocognitive impairment,the mechanisms of HIV-host interaction,HIV-associated dementia,substance abuse,and so on.In the end of this review,we also give some prospects about the limitation and future improvement of HIV/AIDS proteomic research.