Genetic Polymorphisms of Nine X-STR Loci in Four Population Groups from Inner Mongolia, China
- Author:
Hou QIAO-FANG
1
;
Yu BIN
;
Li SHENG-BIN
Author Information
1. Medical College of Xi 'an Jiaotong University
- Keywords:
X chromosome STR;
genetic polymorphism;
genetic distance;
Inner Mongolian populations
- From:
Genomics, Proteomics & Bioinformatics
2007;5(1):59-65
- CountryChina
- Language:Chinese
-
Abstract:
Nine short tandem repeat (STR) markers on the X chromosome (DXS101, DXS6789, DXS6799, DXS6804, DXS7132, DXS7133, DXS7423, DXS8378, and HPRTB) were analyzed in four population groups (Mongol, Ewenki, Oroqen, and Daur) from Inner Mongolia, China, in order to learn about the genetic diversity, forensic suitability, and possible genetic affinities of the populations. Frequency estimates, Hardy-Weinberg equilibrium, and other parameters of forensic interest were computed. The results revealed that the nine markers have a moderate degree of variability in the population groups. Most heterozygosity values for the nine loci range from 0.480 to 0.891, and there are evident differences of genetic variability among the populations. A UPGMA tree constructed on the basis of the generated data shows very low genetic distance betweent Mongol and Han (Xi'an) populations. Our results based on genetic distance analysis are consistent with the results of earlier studies based on linguistics and the immigration history and origin of these populations. The minisatellite loci on the X chromosome studied here are not only useful in showing significant genetic variation between the populations, but also are suitable for human identity testing among Inner Mongolian populations.
