A case of hypophosphatemia rickets with unidentified apical periodontitis as the initial symptom of diagnosis
10.7518/hxkq.2024.2024175
- VernacularTitle:不明原因根尖周炎为首诊症状的低血磷性佝偻病1例
- Author:
Yuan SHI
1
;
Jimei SU
;
Lihua LÜ
;
Dingwen WU
Author Information
1. 浙江大学医学院附属儿童医院口腔科 国家儿童健康与疾病临床医学研究中心,杭州 310052
- Keywords:
X-linked hypophosphatemia rickets;
non-carious teeth;
apical periodontitis
- From:
West China Journal of Stomatology
2024;42(6):832-838
- CountryChina
- Language:Chinese
-
Abstract:
Hypophosphatemia rickets is a rare disease that is divided into two categories,namely,hereditary and ac-quirability.Its clinical manifestations include growth disorders,limb deformities and dysfunction,poor mineralization of the teeth,and growth retardation in children as well as hyperparathyroidism,osteoarthritis,osteomalacia,and pseudofrac-ture in adults.Oral manifestations include non-carious teeth with recurrent apical periodontitis,periapical abscess and even cellulitis,periodontitis,and early tooth loss.X-linked hypophosphatemia rickets(XLHR)accounts for approximate-ly 80％of all hypophosphatemia rickets.We report a 3-year-old child with XLHR whose first diagnosis was apical peri-odontitis of multiple non-carious and non-traumatic teeth.Through medical history,clinical examination,laboratory ex-amination,radiographic findings,genotype testing,and literature analysis,we analyze the pathogenesis,clinical manifes-tations,radiographic features,diagnosis and differential diagnosis,treatment,and follow-up.This work provides refer-ence for clinical diagnosis and treatment and reduces missed diagnosis and misdiagnosis by dentists.
