Design strategy of hydrogel wound dressings based on oral special environment
10.7518/hxkq.2024.2024262
- VernacularTitle:基于口腔特殊环境的水凝胶创面敷贴设计策略
- Author:
Rui XU
1
;
Zhao PAN
;
Duohong ZOU
Author Information
1. 安徽医科大学口腔医学院,安徽医科大学附属口腔医院,安徽省口腔疾病研究重点实验室,合肥 230032
- Keywords:
oral wounds;
hydrogel dressing;
wet adhesion;
mechanical properties;
controlled drug release sys-tems
- From:
West China Journal of Stomatology
2024;42(6):689-698
- CountryChina
- Language:Chinese
-
Abstract:
Oral wounds caused by injuries,surgeries,diseases,and chemical irritations bring pain to the patient and increase the risk of infection.Effective wound protection and repair are crucial for improving patients'quality of life and maintaining oral health.Wound dressings provide ideal healing conditions by isolating the wound from the oral environ-ment.However,in the highly moist,microbiologically rich environment of the oral cavity,maintaining the stability of wound dressings remains a considerable challenge.Hy-drogels show promising prospects for oral applications and are gradually becoming a research hotspot for ad-dressing the challenges of oral wound protection and re-pair due to their excellent biocompatibility and versatile performance.In this paper,the current design strategies of hydrogel wound dressings that overcome the unique oral environment,achieve sustained adhesion and fulfill their functions are reviewed to provide new insights for the de-sign of ideal oral wound barrier materials.
