Systematic review of magnetic resonance imaging in diagnosing mandibular invasion caused by oral cancers
- VernacularTitle:磁共振成像对口腔癌下颌骨骨侵犯诊断价值的系统评价
- Author:
You LI
1
;
Chunjie LI
;
Jun SUN
;
Li YE
;
Yi SU
;
Longjiang LI
Author Information
- Keywords: oral cancer; mandible; invasion; magnetic resonance imaging
- From: West China Journal of Stomatology 2015;(4):423-427
- CountryChina
- Language:Chinese
- Abstract: Objective To?evaluate?the?diagnostic?value?of?magnetic?resonance?(MR)?imaging?in?the?diagnosis?of?mandi-bular?invasion?caused?by?oral?cancers.?Methods???Medline,?EMBASE,?SIGLE,?and?Chinese?biomedical?literature?database?were?searched?electronically.?Manual?searching?for?19?relevant?Chinese?journals?was?also?performed.?Two?reviewers?evaluated?the?literature?and?extracted?the?data.?Meta-Disc?1.4?was?chosen?to?conduct?the?sensitivity?(SEN),?specificity?(SPE),?and?95%?confidence?interval?(95%CI).?Results???Twelve?studies?with?a?total?of?476?patients,?namely,?5?prospective?studies?and?7?retros-pective?studies,?were?included.?All?the?studies?had?unclear?risk?of?bias.?Meta-analysis?result?showed?that?the?combination?of?SEN?of?MR?in?diagnosing?mandibular?invasion?was?0.779?(95%CI:?0.719-0.831),?combination?of?SPE?was?0.823?(95%CI:?0.767-0.870),?positive?likelihood?ratio?was?3.442?(95%CI:?2.181-5.431),?negative?likelihood?ratio?was?0.286?(95%CI:?0.181-0.451),?and?diagnostic?odds?ratio?was?25.702?(95%CI:?13.406-49.273).?The?area?under?curve?was?0.903?9?and?Q*?was?0.835?4.?Meta-analysis?was?not?processed?when?diagnosing?mandibular?medullary?invasion?because?only?two?studies?with?55?patients?had?been?reported.?The?SEN?was?0.838,?and?the?SPE?was?0.722.?Conclusion???MR?is?efficient?and?has?clinical?value?in?the?diagnosis?of?mandibular?invasion?caused?by?oral?cancer.
