Study on the antibacterial activity of four kinds of nano-hydroxyapatite composites againstEnterococcus faecalis
10.7518/hxkq.2015.03.018
- VernacularTitle:4种纳米羟磷灰石复合材料对粪肠球菌抗菌性能的初步研究
- Author:
Yi LIU
1
;
Rongjing ZHOU
;
Hongkun WU
Author Information
1. 四川省医学科学院?四川省人民医院口腔科
- Keywords:
nano-hydroxyapatite;
Enterococcus faecalis;
antibacterial activity
- From:
West China Journal of Stomatology
2015;(3):301-305
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveThis?study?aims?to?compare?and?determine?a?kind?of?nano-hydroxyapatite?composite?material?with?good?antibacterial?efficacy?on?Enterococcus faecalis(E. faecalis)?in vitro.?Methods???We?investigated?the?antimicrobial?acti-vity?of?four?kinds?of?nano-hydroxyapatite?composites,?namely,?silver/hydroxyapatite?composite?nanoparticles?(Ag/nHA),?yttrium/hydroxyapatite?composite?nanoparticles?(Yi/nHA),?cerium/hydroxyapatite?composite?nanoparticles?(Ce/nHA),?and?hydroxyapatite?nanoparticles?(nHA),?against?E. faecalis?in vitro?using?the?agar?diffusion?and?broth?dilution?method?by?mea-suring?the?growth?inhibition?zone?and?the?minimum?inhibitory?concentration?(MIC),?respectively.?Results???The?agar?diffu-sion?test?results?showed?that?Ag/nHA?displayed?an?obvious?growth?inhibition?zone,?whereas?Yi/nHA,?Ce/nHA,?and?nHA?showed?no?influence?on?E. faecalis.?The?MIC?value?of?Ag/nHA?was?1.0?g·L-1,?and?the?three?other?materials?had?no?effect?on?E. faecalis?even?at?the?high?concentration?of?32.0?g·L-1.?Conclusion???Ag/nHA?display?a?potential?antimicrobial?efficacy?to?planktonic?E. faecalis.?Whereas,?the?three?other?kinds?of?nano-hydroxyapatite?composites?(Yi/nHA,?Ce/nHA,?nHA)?show?no?influence.
