Effect observation and nursing of different doses of simvastatin in the treatment of acute myocardial infarction
10.7619/jcmp.201514002
- VernacularTitle:不同剂量辛伐他汀治疗急性心肌梗死的效果观察及护理
- Author:
Chunxaing XIA
1
;
Hua JIANG
;
Jianshu ZHU
;
Junping ZHANG
;
Shuchen LI
;
Shurong LI
Author Information
1. 河北省唐山市丰润区第二人民医院
- Keywords:
dosage;
simvastatin;
acute myocardial infarction;
curative effect;
nursing in-tervention
- From:
Journal of Clinical Medicine in Practice
2015;(14):4-6,10
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of different doses of simvastatin in the treat-ment of acute myocardial infarction,and to explore the nursing countermeasures.Methods A total of 86 patients with acute myocardial infarction in our hospital were as the research objects,and were randomly divided into 2 groups,and all the patients used simvastatin on the basis of conventional treatment.A group with 43 cases was given simvastatin dosage for 20 mg,B group with 43 cases was given simvastatin dosage for 40 mg.Both 2 groups during the treatment were given comprehen-sive nursing intervention.The treatment effect of 2 groups was compared.Results After treat-ment,the total efficiency in A group was 95.4% and 81.4% in B group,the difference in the total efficiency between 2 groups was significant (P <0.05).Before treatment,there was no significant difference in TC,TG,LDL-C and CRP (P >0.05)and the index of group B after the treatment was better that that in the A group (P < 0 .0 5 ).The incidence rate of cardiovascular events was 25.6% in A group and 9.3% in B group,and the incidence rate of cardiovascular events in B group was significantly less than that that in A group (P <0.05).Adverse reaction rate was 11.6% in A group and 16.3% in B group,there was no significant difference between 2 groups (P >0.05). Conclusion The curative effect of higher dose simvastatin in adjuvant treatment of acute myocar-dial infarction is better and it can reduce cardiovascular adverse events,so it is worthy of applica-tion.
