Cord blood stem cell transplantation combined with traditional Chinese therapy for kidney nourishing and dampness elimination in treatment of patients with Child A or B grade liver cirrhosis
10.7619/jcmp.201417008
- VernacularTitle:脐血干细胞移植结合补益肾气利湿法治疗ChildA、B级肝硬化的疗效及机制探讨
- Author:
Xiaoling ZHOU
1
;
Sheng XIE
;
Qiao CHEN
;
Qiuke HOU
Author Information
1. 广西壮族自治区柳州市中医院 消化科
- Keywords:
cord blood stem cell;
transplant;
kidney nourishing;
dampness elimination;
cirrhosis
- From:
Journal of Clinical Medicine in Practice
2014;(17):25-28
- CountryChina
- Language:Chinese
-
Abstract:
Obj ective To observer the clinical effects of cord blood stem cell transplantation combined with traditional Chinese therapy for kidney nourishing and dampness elimination in treat-ment of patients with child A or B grade liver cirrhosis,and related mechanism.Methods 50 pa-tients with child A or B grade liver cirrhosis were randomly divided into treatment group and control group,with 25 cases in each group.Cord blood stem cell transplantation were performed in both of two groups and Chinese therapy for kidney nourishing and dampness elimination was provided to treatment group additionally.Biomedical index of liver function,erythrocyte immune and observed before and 3,6,12 months after surgery.Inflammation and fibrosis score before and 12 months af-ter surgery were also observed.Results Index levels mentioned above were improved after treat-ment compared with those before treatment,and there was significant difference between treatment and controls group (P<0.05,P<0.01 ).Conclusion Combination therapy of transplantation with traditional Chinese therapy can achieve better clinical outcome.