Significance of platelet parameters in the diagnosis and efficacy-evaluation of adult patients with severe primary mmune thrombocytopenia
10.7619/jcmp.201415048
- VernacularTitle:血小板参数在成人重度原发免疫性血小板减少症诊断和疗效判断中的意义
- Author:
Meihua JI
1
;
Jian TAO
;
Jin CHEN
;
Quan HUANG
;
Haijia MA
Author Information
1. 南通大学第二附属医院 血液科
- Keywords:
primary immune thrombocytopenia;
platelet parameter;
clinical significance
- From:
Journal of Clinical Medicine in Practice
2014;(15):140-142
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical significance of detecting platelet parameters in the diagnosis and efficacy-evaluation of adult severe primary immune thrombocytopenia (ITP). Methods Thirty-four adult patients with primary ITP admitted in our hospital served as observa-tion group while another 30 healthy people undergoing physical examination as control group. Platelet parameters on both groups before treatment and in observation group 3and 7 days after treatment were observed.Results Before treatment,observation group was evidently lower in platelet count (PLT)and plateletocrit (PCT)and obviously higher in mean platelet volume (MPV) than control group (P <0.05),but there was no significant difference in platelet distributive width (PDW)(P >0.05).Compared with treatment before,PLT,PCT,MPV increased more markedly 3 d after treatment while PLT,PCT,PDW increased significantly 7 days after treatment in obser-vation group (P <0.05).Conclusion Platelet parameters have important clinical significance in e-valuating the progression and efficacy of adult patients with severe primary ITP.
