Effects of continuous blood purification on extravascular lung water and respiratory function in patients with extrapulmonary acute respiratory distress syndrome

VernacularTitle:连续性血液净化对肺外源ARDS患者肺血管外肺水及呼吸功能的影响
Author: Zhibo LI ¹ ; Deliang WEN ; Weijiang LIU ; Xuming XIONG
Author Information

1. 广州医科大学附属第二医院重症医学科
Keywords: acute respiratory distress syndrome; continuous blood purification; extravaseular lung water
From: Journal of Southern Medical University 2015;(7):1047-1049
CountryChina
Language:Chinese
Abstract: Objective To assess the effects of continuous blood purification (CBP) on extravascular lung water and respiratory function in patients with extrapulmonary acute respiratory distress syndrome (ARDSexp). Methods The data of 31 patients with ARDSexp admitted in our department were retrospectively analyzed.Sixteen of the patients received CBP, and the other 15 patients did not (control group). The level of extravascular lung water index (EVLWI), pulmonary vascular permeability index (PVPI), and respiratory function were measured before and after CPB. Results The mortality rate was significantly lower in CBP group than in the control group (12.5% vs 33.3%, P<0.05). The patients in CPB group showed markedly earlier and significantly greater improvements in EVLWI, PVPI, PaO2/FiO, and respiratory function than the control patients (P<0.05). Conclusion CBP can reduce EVLWI and PVPI, improve pulmonary compliance and oxygenation, and reduce mortality rate in patients with ARDSexp.