Relationship between cardiopulmonary exercise testing and the prognosis of cardiovascular disease in coronary heart disease patients
10.3760/cma.j.cn112148-20231007-00218
- VernacularTitle:心肺运动试验相关指标与冠心病患者心血管疾病预后的关系
- Author:
Yushan LI
1
;
Jian ZHANG
;
Qiang REN
;
Yanchun LIANG
;
Quanyu ZHANG
;
Yaling HAN
Author Information
1. 解放军北部战区总医院心血管内科，沈阳 110016
- Keywords:
Coronary heart disease;
Cardiopulmonary exercise test;
Major adverse cardiovascular events;
Prognosis
- From:
Chinese Journal of Cardiology
2024;52(9):1044-1050
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the predictive value of cardiopulmonary exercise test (CPET) indexes for major adverse cardiovascular events (MACE) in patients with coronary heart disease (CHD).Methods:This study was a retrospective cohort study. CHD patients were consecutively enrolled who procedure CPET before discharge from the Department of Cardiology, General Hospital of Northern Theater Command from November 2015 to September 2021 were enrolled. Demographic information, past medical history, CPET indexes and other baseline data were collected and the patients were followed up. Patients were divided into a MACE group and a control group according to the presence or absence of MACE. A multivariate Cox proportional hazard regression model was used to analyze the CPET indexes with predictive value for MACE in CHD patients.Results:A total of 3 800 patients were eligible for the criterion, age (57.2±8.8) years, 2 920 (76.84%) males. During a follow-up of 1 237 (695, 1 596) days, 390 (10.26%) patients were in MACE group, and 3 410 (89.74%) patients were in control group. In adjusted multivariable analysis, higher metabolic equivalent of tasks (MET) at anaerobic threshold (AT) is an independent protective factor for MACE in patients with CHD ( HR=0.75, 95% CI 0.62-0.90, P=0.002), higher VE/VCO 2 is an independent risk factor for MACE in CHD patients ( HR=1.05, 95% CI 1.02-1.07, P=0.001). Conclusion:In CPET, high MET at AT is an independent protective factor for MACE in patients with CHD, and high VE/VCO 2 is an independent risk factor for MACE in CHD patients.
