Relationship among blood indicators of lipomobilization and hepatic function during early lactation in high-yielding dairy cows.
10.4142/jvs.2011.12.3.251
- Author:
Felix Diaz GONZALEZ
1
;
Rodrigo MUINO
;
Victor PEREIRA
;
Romulo CAMPOS
;
Jose Luis BENEDITO
Author Information
1. Faculdade de Veterinaria, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil. felixgonzalez.ufrgs@gmail.com
- Publication Type:Original Article
- Keywords:
blood biochemistry;
hepatic lipidosis;
high-yielding dairy cow;
ketosis
- MeSH:
3-Hydroxybutyric Acid/blood/diagnostic use;
Animals;
Aspartate Aminotransferases/blood/diagnostic use;
Blood Glucose/analysis/metabolism;
Blood Proteins/analysis/diagnostic use;
Cattle;
Cattle Diseases/blood/*diagnosis;
Fatty Acids, Nonesterified/blood/diagnostic use;
Female;
Ketosis/blood/diagnosis/*veterinary;
Lactation;
*Lipid Mobilization;
Lipidoses/blood/diagnosis/*veterinary;
Liver Function Tests/veterinary;
Spain;
Triglycerides/blood/diagnostic use;
Urea/blood/diagnostic use;
gamma-Glutamyltransferase/blood/diagnostic use
- From:Journal of Veterinary Science
2011;12(3):251-255
- CountryRepublic of Korea
- Language:English
-
Abstract:
Blood indicators are used as a tool to diagnose metabolic disorders. The present work was conducted to study the relationships among blood indicators of lipomobilization and hepatic function in high-yielding dairy cows. Two groups of Holstein cows were studied: 27 early lactation cows and 14 mid lactation cows from four different herds with similar husbandry characteristics in Galicia, Spain. Blood samples were obtained to measure beta-hydroxybutyrate (BHB), non-esterified fatty acids (NEFA), triglycerides (TG), and the activity of aspartate transaminase (AST) and gamma-glutamyl transferase. Cows in early lactation had higher levels of BHB and NEFA than mid lactation cows. High lipomobilization (NEFA > 400 micromol/L) was detected in 67% and 7% of early lactation and mid lactation cows, respectively, while subclinical ketosis (BHB > 1.2 mmol/L) was detected in 41% and 28% of the early lactation and lactation cows, respectively. TG concentrations were low in all cows suffering subclinical ketosis and in 61% of the cows with high lipomobilization. During early lactation, 30% of cows suffered hepatic lipidosis as detected by levels of AST. Compromised hepatic function was observed in early lactation cows as shown by lower concentrations of glucose, total protein, and urea.
