Clinical characteristics of adult Chinese patients with syncope: a multicenter clinical study

Fengjing YANG; Xu LI; Peng LIANG; Zhongmei LIU; Tong LIU; Yun WU; Shuanli XIN; Gaoxing ZHANG; Shilin YAN; Lingping XU; Lixin WANG; Bo HU; Wenwei YUE; Jielin PU; Zhichun HUANG; Rui WANG; Wen WEN; Peihong LIN; Li LI; Zaixin YU; Xiaodong WANG; Xijiu LIU; Jie ZHANG; Xiufen QU; Gary TSE; Yikun PAN; Kui HONG; Jieming ZHU; Lihua LI; Wen PAN; Yong WU; Min WANG; Changjun SONG; Zengshuai WANG; Jianting DONG; Xinchun YANG; Xitian HU; Fujun WANG; Wenling LIU

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Clinical characteristics of adult Chinese patients with syncope: a multicenter clinical study

VernacularTitle:中国成人晕厥患者临床特征分析：一项多中心研究
Author: Fengjing YANG ¹ ; Xu LI ; Peng LIANG ; Zhongmei LIU ; Tong LIU ; Yun WU ; Shuanli XIN ; Gaoxing ZHANG ; Shilin YAN ; Lingping XU ; Lixin WANG ; Bo HU ; Wenwei YUE ; Jielin PU ; Zhichun HUANG ; Rui WANG ; Wen WEN ; Peihong LIN ; Li LI ; Zaixin YU ; Xiaodong WANG ; Xijiu LIU ; Jie ZHANG ; Xiufen QU ; Gary TSE ; Yikun PAN ; Kui HONG ; Jieming ZHU ; Lihua LI ; Wen PAN ; Yong WU ; Min WANG ; Changjun SONG ; Zengshuai WANG ; Jianting DONG ; Xinchun YANG ; Xitian HU ; Fujun WANG ; Wenling LIU
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1. 北京大学人民医院心内科，北京　100044
Keywords: Syncope; Adult; Clinical characteristics
From: Chinese Journal of Cardiology 2022;50(10):1014-1020
CountryChina
Language:Chinese
Abstract: Objective:To analyze the clinical characteristics of adult Chinese patients with syncope.Methods:This is a cross-sectional survey study. Patients with preliminary diagnosis of syncope in the Emergency Department, Geriatrics and Cardiology Outpatient Department, or Syncope Unit of 37 hospitals in 19 provinces, autonomous regions and the Hong Kong Special Administrative Region from June 2018 to March 2021 were included in this study. The clinical features of these patients with syncope were analyzed.Results:A total of 4 950 consecutive patients with syncope were included in this study. The age was (56.3±16.8)years, and 2 604 cases (52.6%) were male. The most common type of syncope was neurally mediated syncope (2 345 (47.4%)), followed by cardiac syncope (1 085 (21.9%)), orthostatic hypotensive syncope (311 (6.3%)), and unexplained syncope accounted for nearly one third (1 155 (23.3%)). Predisposing syncope was more common in patients under 65 years of age(2 066(72.4%) vs. 786(27.6%),χ 2=136.5, P<0.001). Presyncope was more common in patients with neurally mediated syncope (1 972(79.0%) vs.1 908(73.9%), χ 2=17.756, P<0.001). Premonitory symptoms were more common in women(1 837(80.0%) vs. 1 863(73.0%),χ 2=33.432, P<0.001). Presyncope syndrome was more common in patients under 65 years of age (2 482(77.8%) vs. 1 218(73.4%),χ 2=17.523, P=0.001). Cyanosis was more common in ≥65 years old patients (271(18.2%) vs. 369(12.7%), χ 2=23.235, P<0.001). Urinary incontinence was more common in old patients aged ≥65 years(252(15.2%) vs. 345(10.8%), χ 2=19.313, P<0.001). Family history was more common in patients with cardiogenic syncope compared with other types of syncope (264(24.3%) vs. 754(19.5%), χ 2=11.899, P=0.001). Hypertention(1 480(30.5%)), coronary heart disease(1 057(21.4%)), atrial flutter and atrial fibrillation(359(7.2%)), second degree atrioventricular block(236(4.8%)) were common complications of syncope. The proportion of patients with coronary heart disease was significantly higher in cardiac syncope than that of other types of syncope(417(38.4%) vs. 640(16.6%), χ 2=241.376, P<0.001). Other common complications included cerebrovascular diseases (551 (11.1%)) and diabetes mellitus (632(12.8%)). Conclusions:Neurally mediated syncope is the most common syncope in adult Chinese population. Patients with predisposing conditions and premonitory conditions are younger. Presyncope is more common in women. The proportion of family history and coronary heart disease is higher in patients with cardiogenic syncope.