Therapeutic value of intracytoplasmic sperm injection on retrograde ejaculation-induced male infertility
10.7619/jcmp.201413019
- VernacularTitle:卵胞浆内单精子显微注射对逆行射精致男性不育症的治疗价值
- Author:
Xingzhe JI
1
;
Zhou ZHANG
;
Liang ZHOU
;
Hui WANG
;
Xia XUE
;
Xiang LIU
Author Information
1. 陕西省妇幼保健院 辅助生殖中心
- Keywords:
intracytoplasmic sperm injection;
retrograde ejaculation;
infertility;
clinical pregnancy rate
- From:
Journal of Clinical Medicine in Practice
2014;(13):60-62
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical therapeutic value of intracytoplasmic sperm in-jection (ICSI)on retrograde ejaculation-induced male infertility.Methods A total of 10 male pa-tients with retrograde ejaculation-induced male infertility in this center served as research objects. On treatment day,male patients had to urinate immediately after the presence of ejaculation sensa-tion,urine was collected and added with culture medium,centrifuged and cleaned,and directly es-tablish gel to conduct ICSI.As for females,routine gonadotropin-releasing hormone angonist (GnRH-a)was applied to conduct long-protocol controlled ovarian hyperstimulation,and ISCI was conducted for insemination after egg retrival by trans-vaginal puncture.Results All male patients were successfully complete 19-cycle treatment,in which 2 were treated with testicular puncture to collect sperms and ICSI because no movement sperm was found after 4-cycle treatment,while the rest patients finished 15-cycle treatment,including 10 fresh cycles and 5 frozen embryos thawing transplantation (FET)cycles,with total insemination rate,merogenesis rate,clinical pregnancy rate in fresh cycle ,clinical pregnancy rate in FET cycle and total clinical pregnancy rate being 67.97%,94.25%,66.67%,60% and 64.28%,respectively.Conclusion ISCI has certain effi-cacy and is the optimal choice in treating retrograde ejaculation-induced male infertility poor with surgeries.
