Spontaneous renal hemorrhage caused by invasive mole:a case report

VernacularTitle:以肾脏自发破裂为临床表现的侵袭性葡萄胎1例报道
Author: Qingling MU ¹ ; Songshu XIAO ; Yajun WAN
Author Information

1. 中南大学湘雅三医院妇产科
Keywords: invasive mole; metastasis; renal; brain; chemotherapy
From: Journal of Southern Medical University 2015;(2):309-311
CountryChina
Language:Chinese
Abstract: Gestational trophoblastic tumors (GTTs) are malignant lesions that often cause abnormal genital bleeding and may present with hemoptysis, intraperitoneal bleeding or acute neurologic deficits. GTTs are generally highly chemosensitive with more favorable outcomes than other comparable malignancies. Here we report a rare case of invasive mole (FIGO stage IV, WHO score16) presenting with renal subcapsular hematoma due to bleeding renal metastasis. The patient had a pretreatmentβ-human chorionic gonadotrophin (β-HCG) level of 462 047 mIU/ml and received combined chemotherapy with etoposide, methotrexate, actinomycin-D, cyclophosphamide and vincristine with also adjuvant surgeries including hysterectomy and nephrectomy. The patient recovered well and the tumor has remained in complete remission for one year and a half.