Five Cases of Permanent Alopecia Following Chemotherapy.
- Author:
Jee Young PARK
1
;
Yoon Seok CHOI
;
Weon Ju LEE
;
Seok Jong LEE
;
Gun Yoen NA
;
Do Won KIM
Author Information
1. Department of Dermatology, Kyungpook National University School of Medicine, Daegu, Korea. seokjong@knu.ac.kr
- Publication Type:Case Report
- Keywords:
Permanent alopecia;
Chemotherapy;
Busulphan
- MeSH:
Alopecia*;
Bone Marrow Transplantation;
Busulfan;
Drug Therapy*;
Hair;
Incidence;
Korea;
Risk Factors
- From:Korean Journal of Dermatology
2005;43(10):1365-1370
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
With the development of chemotherapeutic agents and bone marrow transplantation, high dose conditioning chemotherapy before bone marrow transplantation, such as busulphan, have become more widely used. Of the side effects following chemotherapy, the cutaneous side effects of hair loss occur in high incidence. Alopecia following chemotherapy was generally known to recover completely in spite of subtle changes to the hair shaft. However, we recently experienced five cases of permanent incomplete regrowth of hair after cessation of conventional chemotherapy or high dose conditioning chemotherapy. In Korea, permenant alopecia following chemotherapy has not yet been reported and we reviewed them with the possible risk factors such as duration and kind of chemotherapeutic agents.
