Risk factors of cardiac rupture in patients with acute myocardial infarction
10.3760/cma.j.issn.0253-3758.2016.10.007
- VernacularTitle:急性心肌梗死后心脏破裂的危险因素分析
- Author:
Zijin LIU
1
;
Huangtai MIAO
;
Shaoping NIE
Author Information
1. 100029,首都医科大学附属第六临床医学院
- Keywords:
Myocardial infarction;
Heart rupture;
Risk factors
- From:
Chinese Journal of Cardiology
2016;44(10):862-867
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the risk factors of cardiac rupture in patients with acute myocardial infarction.Methods Clinical data were analyzed from 10 284 acute myocardial infarction patients admitted to Beijing Anzhen Hospital from January 2012 to March 2015.Cardiac rupture occurred in 81 patients,including 67 patients of acute left ventricular free wall rupture and 14 patients of ventricular septal defect,were retrospectively analyzed.Binary logistics regression analysis was performed to analyze the risk factors of cardiac rupture.Results Incidence of cardiac rupture was significantly higher in patients with ST-segment elevation myocardial infarction than in patients with non-ST-segment elevation myocardial infarction (1.5％ (70/4 724) vs.0.2％ (11/5 560),P ＜0.01).Binary logistic regression analysis showed that age (OR =0.827,95％ CI 0.726-0.941,P ＜ 0.01),recurrent myocardial infarction during hospital (OR =0.001,95％ CI 0.000-0.418,P ＜ 0.05),systolic blood pressure (OR =1.114,95％ CI 1.029-1.206,P ＜ 0.01),left anterior descending artery lesion (OR =0.003,95 ％ CI 0.000-0.334,P ＜ 0.05),lower hemoglobin(OR =1.129,95％ CI 1.051-1.212,P ＜ 0.01),serum total protein (OR =1.453,95％ CI 1.070-1.971,P ＜ 0.05),and serum magnesium level (OR =0.000,95 ％ CI 0.000-0.001,P ＜ 0.01) were associated with cardiac rupture.Conclusion Older age,recurrent myocardial infarction,lower systolic blood pressure,left anterior descending artery lesion,lower serum hemoglobin,lower serum total protein,and higher serum magnesium level are risk factors of cardiac rupture and these factors should be carefully managed to prevent the occurrence of cardiac rupture.
