Association between ambulatory arterial stiffness index with left ventricular mass index in the elderly hypertensive patients
10.3760/cma.j.issn.0253-3758.2016.09.004
- VernacularTitle:老年高血压患者动态动脉硬化指数与左心室质量指数的相关性
- Author:
Huihe CHEN
1
;
Yanshu SUN
;
Meilin LIU
Author Information
1. 100034,北京大学第一医院老年科
- Keywords:
Hypertension;
Aged;
Atherosclerosis;
Cardiomegaly
- From:
Chinese Journal of Cardiology
2016;44(9):750-753
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between ambulatory arterial stiffness index (AASI) and left ventricular mass index (LVMI) in the elderly hypertensive patients.Methods This study population consisted of 332 elderly hypertensive patients,who hospitalized in our department from January 2012 to December 2014.AASI was calculated from 24 h ambulatory BP monitoring recordings and LVMI from echocardiography examination.According to the median value of AASI,patients were divided to less than the AASI median group (low AASI group) and equal to or above the AASI median group (high AASI group).Differences between two groups were evaluated using the Student's t-test and Chi-square test.Univariate association was assessed by the Pearson correlation analyses.Multivariate linear regression models were performed to analyze the correlation between AASI and LVMI.Results LVMI was significantly higher in high AASI group compared with low AASI group ((115.91 ±21.36) g/m2 vs.(104.11 ± 17.24) g/m2,P =0.008).Pearson correlation analyses showed that AASI and 24 h pulse pressure were positively correlated to LVMI (r =0.332,P ＜ 0.001;r =0.169,P =0.002).In multivariate linear regression model,AASI(β =44.48,P＜0.001),LDL-C(β =-5.97,P＜0.001) and UA (β =0.02,P =0.045) showed significant association with LVMI.Conclusion AASI independently associated with LVMI,and AASI might be one predictor of left ventricular hypertrophy in hospitalized elderly hypertensive patients.
