Epidemiologic characteristics of oral cancer：single-center analysis of 4097 patients from the Sun Yat-sen University Cancer Center
10.1186/s40880-016-0078-2
- Author:
Zhang JI
1
;
Gao FAN
;
Yang ANKUI
;
Chen WENKUAN
;
Chen SHUWEI
;
Li HUAN
;
Zhang XING
;
Yang ZHONGYUAN
;
Chen XINLIN
;
Song MING
Author Information
1. State Key Laboratory of 0ncology in South China
- Keywords:
Oral cancer;
Epidemiology;
Guangdong
- From:Chinese Journal of Cancer
2016;35(4):190-195
- CountryChina
- Language:Chinese
-
Abstract:
Background: Oral cancer is a common type of head and neck cancers. Knowing its epidemiologic characteristics is crucial to preventing, diagnosing, and treating this cancer. This study aimed to explore the epidemiologic characteris?tics of oral cancer in South China. Methods: We retrospectively analyzed data from 4097 oral cancer patients treated at the Sun Yat?sen University Cancer Center between 1960 and 2013. We compared the age of onset, sex ratio, pathologic type, and primary tumor location among three subcultural areas (Guangfu, Hakka, and Chaoshan) and between an economically developed region and a less?developed one in Guangdong. Results: Overall, oral cancer had a male?to?female ratio of approximately 2:1, and this ratio decreased over time. Oral cancer occurred mostly in patients of 45–64 years old (54.5%), and the percentage of older patients gradually increased over time. The most common tumor location was the tongue. Squamous cell carcinoma was the predomi?nant pathologic type. The percentage of blood type O in oral cancer patients was lower than that in the healthy pop?ulation. The male?to?female ratio in the Chaoshan area was higher than that in the Guangfu and Hakka areas, whereas the age of disease onset in Guangfu was higher than that in Hakka and Chaoshan. The male?to?female ratio was lower and the age of disease onset was higher in the economically developed region than in the less?developed region. Conclusion: The incidence of oral cancer in South China presents typical characteristics to which doctors should pay attention when diagnosing and treating oral cancer patients.
