Efficacy of intra-aortic balloon counterpulsation in patients with acute myocardial infarction according to the type of revascularization: a meta-analysis
10.3760/cma.j.issn.0253-3758.2016.07.007
- VernacularTitle:主动脉内球囊反搏对接受不同血管重建急性心肌梗死患者预后影响的荟萃分析
- Author:
Zhiwei GAO
1
;
Yingzi HUANG
;
Hongmei ZHAO
;
Hong SUN
Author Information
1. 223300,南京医科大学附属淮安第一医院急诊科
- Keywords:
Myocardial infarction;
Intra-aortic balloon counterpulsation;
Mortality
- From:
Chinese Journal of Cardiology
2016;44(7):588-593
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effects of intra-aortic balloon counterpulsation (IABP) on mortality in patients with acute myocardial infarction according to the type of revascularization.Methods Recruited randomized controlled trials of IABP compared with no-IABP controls in acute myocardial infarction patients from January 1970 to May 2015 were searched from Medline,Embase and Cochrane Library,according to inclusion criteria and exclusion criteria.These data were analyzed using the methods recommended by the Cochrane Collaboration's software RevMan 5.0.Revascularization included thrombolytic therapy,percutaneous coronary intervention (PCI),or coronary artery bypass grafting.Results (1) Eleven randomized controlled trials were enrolled for analysis with 1 102 patients in IABP group,1 123 in no-IABP control group.(2) Compared with no-IABP control group,IABP could not significantly decrease the in-hospital or 30 day mortality (OR =0.84,95％ CI 0.65-1.09,P =0.20).(3) Compared with no-IABP control group,IABP could not significantly decrease the in-hospital or 30 day mortality in thrombolytic patients(OR =0.64,95％ CI 0.25-1.61,P =0.34),in PCI patients (OR =0.89,95％ CI 0.68-1.18,P =0.42),and in coronary artery bypass grafting patients (OR =0.46,95％ CI 0.13-1.63,P =0.23).(4) The difference reached borderline signiicance between no-IABP control group and IABP group in patients using IABP before PCI(OR =0.47,95％ CI 0.22-1.00,P =0.05),but not in case of after PCI(OR =1.33,95％ CI 0.63-2.79,P =0.45).Conclusions IABP does not decrease the in-hospital or 30 day mortality of acute myocardial infarction patients who received thrombolytic therapy,PCI,or coronary artery bypass grafting.But IABP might decreases the in-hospital or 30 day mortality in patients when used before PCI.
