Influence of peritoneal lavage therapy at different time on efficacy of severe acute pancreatitis patients with intra-abdominal hypertension

VernacularTitle:不同时机腹腔灌洗治疗对重症急性胰腺炎并腹腔高压患者疗效的影响
Author: Guishan YE ¹ ; Jun XIAO ; Rong XHONG ; Jianhua TANG
Author Information

1. 桂林医学院附属医院重症医学科
Keywords: severe acute pancreatitis; intra-abdominal hypertension; time; peritoneal lavage
From: Journal of Clinical Medicine in Practice 2014;(9):88-89,92
CountryChina
Language:Chinese
Abstract: Objective To explore the influence of peritoneal lavage therapy at different time on efficacy of severe acute pancreatitis (SAP)patients with intra-abdominal hypertension (IAH). Methods 68 SAP patients with IAH were divided into 3 groups according to time of peritoneal lavage therapy,including group A (n =20,≤24 hours),group B (n =26,>24 hours~≤ 48 hours)and group C (n =22,>48 hours~≤72 hours).APACHE-Ⅱscore was calculated and in-tra abdominal pressure (IAP)was measured before treatment and 7 days after peritoneal lavage therapy.Results APACHE-Ⅱscore and IAP 7 days after peritoneal lavage therapy in all groups decreased significantly (P <0.01).Along with the time delay of peritoneal lavage,the decline of APACHEII score and IAP 7 days after peritoneal lavage decreased gradually (P <0.05).7 days af-ter peritoneal lavage treatment,the degree of decline of IAP in group A was significantly greater than group B (P <0.05).Conclusion Application of peritoneal lavage therapy within 24 hours is the best time for treatment of SAP patients with IAH.