Application of thinprep cytology in the diagnosis of thyroid nodules by thyroid fine needle aspiration
10.7619/jcmp.201409007
- VernacularTitle:液基薄层细胞学技术在甲状腺细针穿刺诊断甲状腺结节中的应用研究
- Author:
Dongxiang XU
1
;
Qinghua YOU
;
Aihua WANG
;
Huiying YE
;
Jun ZHANG
;
Min YE
Author Information
1. 复旦大学附属浦东医院 内分泌科
- Keywords:
thinprep cytology;
fine needle aspiration;
thyroid
- From:
Journal of Clinical Medicine in Practice
2014;(9):27-30
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the value of thinprep cytology in the diagnosis of thyroid nodules by thyroid fine needle aspiration.Methods Liquid-based thin-film cell production technology (TCT)and traditional producers technology (CS)were used in detection of 125 specimens by thyroid fine needle aspiration.Results TCT had the following characteristics :significant increased in cell number,cell morphology clear structure could be clearly observed especially pleomorphic nuclei,elon-gated or irregular nuclear membrane,nuclear grooves and nuclear inclusions,the cells showed a single layer arrangement,smear clean background,less blood cells and impurities.TCT and CS differences in the classification of cytologic diagnosis was obvious (χ2 =7.727,P =0.052 >0.05).TCT results in line with the pathological diagnosis was 98.9%,which was higher than CS and pathological diagno-sis compliance rate of 90.3% (χ2 =6.764,P =0.009 <0.05).Accuracy,sensitivity and specificity in TCT group were better than CS (P <0.01).Conclusion TCT producers can improve the quality of thyroid biopsy,sensitivity,specificity and accuracy of pathological diagnosis coincidence rate,so it is worthy of clinical application and popularization.
