Changes of C-reactive protein level and inflammatory factors in patients with obstructive sleep apnea syndrome
10.7619/jcmp.201409005
- VernacularTitle:C-反应蛋白水平及炎性因子变化在阻塞性睡眠呼吸暂停低通气综合征C-反应蛋白水平及炎性因子变化中的价值观察及分析
- Author:
Minjing LI
1
;
Guocui XHEN
;
Yeliang WEN
;
Shaozhi HU
Author Information
1. 广东省佛山市第一人民医院 呼吸内科
- Keywords:
C-reactive protein;
interleukin-6;
interleukin-18;
obstructive sleep apnea syndrome
- From:
Journal of Clinical Medicine in Practice
2014;(9):19-21,30
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe and analyze the changes of C-reactive protein and inflam-matory factors in patients with obstructive sleep apnea syndrome.Methods 205 patients with ob-structive sleep apnea syndrome were divided into observation group Ⅰ (n =72),group Ⅱ (n =68) and observation group Ⅲ (n =65)according to apnea-hypopnea index (AHI),and the other 50 pa-tients were designed as control group.Levels of C-reactive protein,interleukin-6 and interleukin-18 were detected.Results The sicker,apnea-hypopnea index gradually increased (AHI),oxygen sat-uration decreased,C-reactive protein,interleukin-6 and interleukin-18 levels increased gradually. Logistic regression analysis showed that C-reactive protein,interleukin-6 and interleukin-18 and AHI,oxygen saturation were positively correlated with AHI and negatively correlated with oxygen saturation.Conclusion C-reactive protein level,interleukin-6 and interleukin-18 and other related inflammatory factors are the important indicators for prognosis judgment of patients with obstructive sleep apnea syndrome,so it is worthy of clinical application.
