Extraskeletal Ewing's sarcoma: a report of 18 cases and literature review
- VernacularTitle:18例骨外Ewing肉瘤的临床分析并文献复习
- Author:
Xie CHUN-FANG
1
,
2
,
3
;
Liu MENG-ZHONG
;
Xi MIAN
Author Information
1. 华南肿瘤学国家重点实验室,广东,广州,510060
2. 中山大学肿瘤防治中心放射治疗科,广东,广州,510060
3. 广东佛山三水区人民医院肿瘤科,广东,佛山,528100
- Keywords:
Extraosseous Ewing's sarcoma;
clinical feature;
diagnosis;
treatment
- From:Chinese Journal of Cancer
2010;29(4):462-467
- CountryChina
- Language:Chinese
-
Abstract:
Background and Objective: Extraskeletal Ewing's sarcoma(EES)is a rare,rapidly growing,round-cell,malignant tumor that can develop in the soft tissues at any location.This study was to analyze the clinical features,diagnosis and treatment of EES.Methods: Clinical data of 18patients with EES,treated at Sun Yat-sun University Cancer Center between1995 and 2007,were analyzed.Reults: Of the 18 patients,13 were male and 8 were female,aged from 8 months to 60 years.Twelve(66.7%)patients were between 5-25 years of age.Eight(44.4%)patients had tumors originated from low extremities.Sixteen patients had masses at their first visit.Sixteen patients were treated by the combined modality therapy,and 2 patients were treated by the single modality therapy.The 1-,3-and 5-year actuarial survival rates were 82.4%,64.2% and 32.1%,respectively.The presence of metastatic disease at the time of diagnosis and the mode of treatment were prognostic factors.Conclusions: EES is common in adolescent.It often manifests as a localized mass.The combined modality therapy is recommended for this disease.The presence of metastatic disease at the time of diagnosis and the mode of treatment are prognostic factors.
