Lung Transplantation in ABO Compatible but Nonidentical Patients.
- Author:
Song Hyeon YU
1
;
Hae Kyoon KIM
;
Doo Yun LEE
;
Hyo Chae PAIK
;
Hwa Kyun SHIN
;
Yun Joo HONG
;
Bu Yun KIM
;
Eung Suk LEE
;
Jae Young KIM
Author Information
1. Department of Thoracic & Cardiovascular Surgery Youngdong Severance Hospital Yonsei University, Korea.
- Publication Type:Case Report
- Keywords:
Lung transplantation;
Blood type
- MeSH:
Adult;
Azathioprine;
Dyspnea;
Emphysema;
Female;
Humans;
Immunosuppression;
Immunosuppressive Agents;
Lung Transplantation*;
Lung*;
Male;
Survival Rate;
Tissue Donors
- From:The Korean Journal of Thoracic and Cardiovascular Surgery
2001;34(1):94-96
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Lung transplantation in the treatment of end-stage emphysema has been increasing in number since the recent rise in the 5 year survival rate. For the shortage of donor lungs, the single lung transplantation or transplantation in ABO compatible, nonidentical recipients has also been increasing. The lung transplantation in compatible, nonidentical recipients show good results as with identical recipients with the proper application of immunosuppressive agents. We transplanted the left lung of a 41 year-old male donor to a 35 year-old female recipient who had been suffering from severe dyspnea due to end-stage emphysema. For postoperative immunosuppression, we applied conventional triple immunotherapy(cyclosporine, azathioprine, prednisolone) and we could suppress the rejection response of transplanted lung by adding the anti-CD3 antibody(OKT3) during the operation. The patient could be discharged without any specific problem at 18th postoperative day.
