Evaluation of a heart-type fatty acid-binding protein detection kit for dignosis of acute coro-nary syndrome
10.3969/j.issn.1673-4254.2014.06.29
- VernacularTitle:人心脏型脂肪酸结合蛋白检测试剂盒诊断急性冠状动脉综合征的价值
- Author:
Yawei LIU
1
;
Miao TIAN
;
Xinzhi JIANG
;
Jiakun LUO
;
Zhiyong YI
Author Information
1. 解放军总参谋部警卫局保健处
- Keywords:
heart type fatty acid binding protein;
diganosis;
acute coronary syndrome
- From:
Journal of Southern Medical University
2014;(6):901-903
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluation the performance of a heart-type fatty acid-binding protein (H-FABP) ELISA detection kit in the clinical diagnosis of acute coronary syndrome (ACS). Methods Plasma or serum samples from 160 suspected ACS patients hospitalized in General Hospital of PLA were examined using Lanzhou H-FABP reagent kit and Holland H-FABP kit. Correlation of the two kits was evaluated and Kappa test was used to examine the consistency of the results of the two products. Results The sensitivity of H-FABP diagnosis of ACS detection Lanzhou kit was 91.8%, the specificity was 88.7%, and the total diagnostic rate was 90.42%. The sensitivity of H-FABP diagnosis of ACS detection Holland kit was 90.3%, the specificity was 86.8%, and the total diagnostic rate was 88.75%. The test results showed that two products yielded comparable results (P=0.668,>0.05) with a good consistency (Kappa=0.726, P<0.01). Conclusions H-FABP ELISA detection kit produccted by LanZhou biological research institute has a good correlation with H-FABP detection kit produced by HBT company of Holland and has the potential for clinical application.
