Research progress in cancer stem cells and their drug resistance
- VernacularTitle:肿瘤干细胞及其耐药性的研究进展
- Author:
Yu HONG
1
;
Zhang CHANG-MING
;
Wu YONG-SHOU
Author Information
1. 云南省第二人民医院
- Keywords:
Stem cells;
cancer stem cells;
drug resistance
- From:Chinese Journal of Cancer
2010;29(3):279-283
- CountryChina
- Language:Chinese
-
Abstract:
Traditional theories suggest that tumor growth occurs when all tumor cells work together and result in proliferation,so treatment has been mainly directed against the majority of the cells in tumor tissue.which often relapse,metastasize,and Iead to treatment failure.As cancer stem cells have been successfully isolated from different tumor tissues,in-depth study of their function in relation to traditionaI cancer treatment faces enormous challenges.At the same time.a new theoretical basis has been provided for the in-depth study of tumorigenesis and the evaluation of prognosis of cancer therapy.Also,new ideas have been introduced for cancer therapy.Therefore,radical treatment of cancer can be achieved through killing cancer stem cells.This article reviews the research progress on cancer stem cells and their drug resistance.
