Dosimetric Characteristics of a Thermal Neutron Beam Facility for Neutron Capture Therapy at HANARO Reactor.
- Author:
Dong Han LEE
1
;
Mi Sook KIM
;
Soheigh SUH
;
Young Hoon JI
;
Moon Sik CHOI
;
Jae Hong PARK
;
Kum Bae KIM
;
Seung Yul YOO
;
Myong Seop KIM
;
Byung Chul LEE
;
Ki Jung CHUN
;
Jae Won CHO
Author Information
1. Radiation & Medical Science Research Center.
- Publication Type:Original Article ; Clinical Trial
- Keywords:
Neutron capture therapy;
HANARO reactor;
Neutron dosimetry;
Ionization chamber
- MeSH:
Fast Neutrons;
Neutron Capture Therapy*;
Neutrons*;
Relative Biological Effectiveness;
Water
- From:Korean Journal of Medical Physics
2007;18(2):87-92
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A thermal neutron beam facility utilizing a typical tangential beam port for Neutron Capture Therapy was installed at the HANARO, 30 MW multi-purpose research reactor. Mixed beams with different physical characteristics and relative biological effectiveness would be emitted from the BNCT irradiation facility, so a quantitative analysis of each component of the mixed beams should be performed to determine the accurate delivered dose. Thus, various techniques were applied including the use of activation foils, TLDs and ionization chambers. All the dose measurements were performed with the water phantom filled with distilled water. The results of the measurement were compared with MCNP4B calculation. The thermal neutron fluxes were 1.02E9 n/cm2 s and 6.07E8 n/cm2 s at 10 and 20 mm depth respectively, and the fast neutron dose rate was insignificant as 0.11 Gy/hr at 10 mm depth in water. The gamma-ray dose rate was 5.10 Gy/hr at 20 mm depth in water. Good agreement within 5%, has been obtained between the measured dose and the calculated dose using MCNP for neutron and gamma component and discrepancy with 14% for fast neutron flux. Considering the difficulty of neutron detection, the current study support the reliability of these results and confirmed the suitability of the thermal neutron beam as a dosimetric data for BNCT clinical trials.
