Analysis of cervical and retropharyngeal lymph node metastases in the patients with hypopharyngeal carcinoma with computed tomography and magnetic resonance imaging
- VernacularTitle:下咽癌颈部及咽后淋巴结转移的CT/MRI分析
- Author:
Deng XUE-YING
1
,
2
;
Su YONG
;
Zheng LIE
;
Xie CHUAN-MIAO
;
Gu MO-FA
;
Zeng RUI-FANG
;
Yin SHAO-HAN
Author Information
1. 华南肿瘤学国家重点实验室,广东,广州510060
2. 中山大学肿瘤防治中心放疗科,广东,广州,510060
- Keywords:
Hypopharyngeal neoplasm;
cervical neoplasm/lymph node: retropharyngeal lymph node;
CT;
MRI
- From:Chinese Journal of Cancer
2010;29(2):202-206
- CountryChina
- Language:Chinese
-
Abstract:
Background and Objective:Hypopharyngeal carcinoma has a high risk for early regional lymphatic dissemination.However.reports about regional lymph node metastases, especially retropharyngeal lymph node metastases,are rare.This research explored the spread of hypopharyngeal carcinoma, especially metastases of the retropharyngeal lymph nodes by studying computed tomography(CT) and magnetic resonance imaging (MRI) images. Methlods:The CT/MRI images of 88 patients with pathologically confirmed hypOpharyngeaI carcinomas that were performed at our hospital between August 2000 and March 2009 were analyzed retrospectively.The interrelations among local stage and lymph nodes in vanous regtons were analyzed by χ~2 test and multivariate logistical regression. ResulIts:The rate of regional lymph node metastasis for all patients was 73.9%.and the highest rates of positive lymph nodes were at levels 11 a(61.4%),11 b(44.3%),and Ⅲ (37.5%).Metastases to levels Ⅰ,Ⅳ,Ⅴ,and Ⅵ were rare,as were retropharyngeal lymph-node metastases,which were always combined with metastases at levels Ⅱ and Ⅲ.Univariate analysis showed that level-Ⅳ metastases correlated to metastases at levels Ⅰ b and Ⅲ:retropharyngeal lymph node metastases were correlated to level Ⅱ b and bilateral cervical lymph node metastases. Multivariate analysis showed that level-Vl metastases correlated to level Ⅳ and that retropharyngeal lymph-node metastases correlated to bilateral cervical lymph node metastases.Conclusions:Regional lymph node metastases in patients with hypopharyngeal carcinoma follow some regulations,and skip metastasis is rare.The highest rates of positive lymph nodes are at levels Ⅱ and Ⅲ.Bilateral lymph node metastases may be a risk factor for retropharyngeallymph node metastases.
