A Case of Thyrotropin (TSH)-Secreting Pituitary Adenoma in a Patient with Ankylosing Spondylitis.
10.3904/kjm.2015.88.6.737
- Author:
Ji Heh PARK
1
;
Seung Geun LEE
;
Eun Kyoung PARK
;
Dong Wan KOO
;
Bo Hyun KIM
;
In Joo KIM
;
Geun Tae KIM
Author Information
1. Department of Internal Medicine, Pusan National University School of Medicine, Busan, Korea. sglee@pnuh.co.kr
- Publication Type:Case Report
- Keywords:
Pituitary neoplasms;
Thyrotropin;
Spondylitis, Ankylosing
- MeSH:
Adult;
Humans;
Hyperthyroidism;
Incidence;
Magnetic Resonance Imaging;
Male;
Pituitary Neoplasms*;
Rheumatic Diseases;
Skeleton;
Spondylitis, Ankylosing*;
Thyroid Diseases;
Thyrotropin*;
Thyrotropin-Releasing Hormone;
Uveitis, Anterior
- From:Korean Journal of Medicine
2015;88(6):737-741
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A thyrotropin (TSH)-secreting pituitary adenoma is a rare cause of hyperthyroidism, with an incidence of one case per million. Ankylosing spondylitis (AS) is a chronic inflammatory rheumatic disease of the axial skeleton. Extra-articular manifestations, such as anterior uveitis, may also be prominent features in AS but little is known about the association between AS and thyroid diseases including TSH-secreting pituitary adenomas. We present a case study of a 26-year-old male AS patient who was diagnosed with a TSH-secreting pituitary adenoma using a thyrotropin releasing hormone stimulation test, measurement of the TSH alpha-subunit, and magnetic resonance imaging, and subsequently treated with a transsphenoidal tumor resection.