Research and surveillance on population of post-exposure prophylaxis for rabies in Shandong province
10.3760/cma.j.cn112866-20240524-00088
- VernacularTitle:山东省狂犬病暴露人群监测研究
- Author:
Xiaomei ZHANG
1
;
Xueying TIAN
;
Qing DUAN
;
Bo PANG
;
Yuwei ZHANG
;
Zengqiang KOU
;
Wenji ZHAI
;
Shujun DING
Author Information
1. 山东省疾病预防控制中心 山东省传染病预防控制重点实验室，济南 250014
- Keywords:
Rabies;
Exposure;
Surveillance;
Post-exposure prophylaxis
- From:
Chinese Journal of Experimental and Clinical Virology
2024;38(4):378-382
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the surveillance data of population in rabies exposure and post-exposure prophylaxis (PEP) clinics in Shandong province from 2019 to 2023, explore risk factors for exposure, and provide a basis for further standardizing PEP.Methods:Based on surveillance data from the rabies exposure treatment clinic vaccination information system, population, and spatial administrative division data in Shandong province from 2019 to 2023, descriptive epidemiological methods were applied to analyze using SPSS 18.0.Results:The number of individuals receiving post-exposure treatment at PEP clinics in Shandong province from 2019 to 2023 was over 1 million annually and showed an increasing trend year by year, with the highest number of visits occurring from May to August each year. The number of female patients is increasing year by year. The 15-year-old and younger age group accounted for 31.69%-36.86% of clinic visits. Grade Ⅲ exposures accounted for 53.40%, and limbs accounted for approximately 89.81% of exposed areas. Approximately 1.94% is multi site exposure. The main injuring animals were dogs, followed by cats, and the proportion of cats is increasing year by year. The proportion of doctor′s office visitors who self-treated wounds increased from 32.32% to 45.46%, while the proportion of outpatient wound treatment decreased from 76.07% to 66.24%. The whole course vaccination rate after initial exposure is 63.79%. The whole course vaccination rate for the 15-29-year-old age group was lower than that for other age groups. The usage rate of passive immune preparations among grade Ⅲ exposed individuals is 35.66%. From 2019 to 2023, 8 cases of rabies were reported, none of whom received standard post-exposure treatment.Conclusions:The epidemic characteristics and exposure risk of people exposed to suspected rabies animals in Shandong province have changed. It is necessary to pay attention to the female population, the population with low vaccination rate between 15 to 29 years of age, cat bitten people, and carry out continuous monitoring on the exposed population, and timely adjust the prevention and control strategies.
